| What is Renal Failure? | | | | creatinine concentration and BUN levels decreased; |
| If you or someone you love suffers from | | | | additionally, urine production improved from 1,300 to |
| progressive, chronic renal failure (CRF) or end-stage | | | | 1,920 ml. Other non-dialysis participants who were |
| kidney failure, you understand how vital these organs | | | | treated with CoQ10 also showed significant |
| are to human life. (Its most common cause attributed | | | | improvement; while hemodialysis placebo users |
| to diabetes.) When an individual reaches end-stage | | | | displayed worsened renal function. Overall, CoQ10 |
| kidney disease, the kidneys are nearly or totally | | | | proved to be positively responsive to eighty-one |
| incapable of functioning.Most persons who encounter | | | | percent of study participants.Per the Study's author, |
| renal failure are very familiar with Creatinine | | | | (Dr. Singh), CoQ10 is most effective in patients who |
| (excreted in urine as metabolic wastes) and BUN | | | | produced no less than 1,000/ml of urine (with or |
| (blood urea nitrogen - protein metabolism breakdown | | | | without the aid of furosemide) daily. Unfortunately, |
| product in the blood) tests, and comprehend | | | | CoQ10 is not as efficient when urine output has |
| devastating effects that these metabolic results can | | | | already decreased to less than 500/ml per day. (This |
| have on the kidneys, liver, heart and other organs as | | | | is more than likely due to irreversible kidney |
| well. In end-stage renal failure, Creatinine and BUN | | | | damage.)While larger, controlled research trials are still |
| levels become persistenly high.When this occurs, the | | | | necessary, the study recommends renal failure |
| kidneys can no longer concentrate urine, excrete | | | | patients take 180 mg of CoQ10 daily; however, it is |
| wastes or regulate electrolytes (electrically charged | | | | always in the patient's best interest to check with his |
| minerals in the blood and other bodily fluids); which in | | | | her healthcare provider for dosages and for any |
| turn causes the body to accumulate fluids and waste | | | | possible drug interactions. In closing, CoQ10 seemingly |
| products. The severe nature of this disease can | | | | provides much-needed hope to naturally improve |
| cause multiple and severe complications, as well as | | | | overall kidney function.Disclaimer: |
| death; unless strictly treated with long-term dialysis (a | | | | Information provided by is intended for educational |
| procedure that removes metabolic waste products | | | | purposes only and should never substitute advice |
| from the body) and until eventual kidney | | | | provided by a licensed health |
| transplantation can be performed.Promising Research | | | | professional.References:Townsend Letter: Report - |
| According to an informative report in the Townsend | | | | Coenzyme Q10 for chronic renal failureStudy |
| Letter, a 12-week, double-blind study on CoQ10 was | | | | Resource: Singh RB, et.al. Randomized, double-blind, |
| performed on ninety-seven patients with end-stage | | | | placebo-controlled trial of coenzyme CoQ10 in |
| renal failure. Participants averaged 48 years of age | | | | patients with end-stage renal failure. Journal of |
| and were indiscrimately given either placebo or 60mg | | | | Nutritional and Environmental Medicine 2003; |
| of CoQ10 orally, three (3) times daily. Initially, a little | | | | 13:13-22Bastyr Center for Natural Health Report - |
| less than half of the participants (45) were using | | | | Coenzyme Q10 Good for People with Kidney Failure, |
| hemodialysis from the onset of the study. These | | | | by Alan R. Gaby, MD - Healthnotes, Inc.Renal Failure: |
| patients were motivated to either reduce or stop | | | | CoQ10 May Improve Kidney Function |
| dialysis to determine any reduction in creatinine levels | | | | Copyright 2005 - All Rights Reserved |
| and increased urine output.Study results found that | | | | Report by C. |