General information on Bird Flu

Bird flu is a disease caused by type "A" influenzainfluenza viruses (H1N1, H1N2, and H3N2). There is the
viruses.possibility that these subtypes to have came from
Wild birds are a natural reservoir of type A of flubirds originally and scientists worry about the
virus, but they are not affected by it. They canpossibility that the bird flu viruses to mutate and
infect domestic birds such as chicken or turkey,transmit from human to human.
which get ill and die.Some symptoms of bird flu infection on humans are:
Birds get infected if they get in contact withfever, lethargy, sore throat, breathing problems,
secretions or excretions of the affected birds, withconjunctivitis, muscle aches and cough.
contaminated water or food and even withStudies suggest that antiviral drugs used against
contaminated surfaces (dirt and cages).human influenza might be useful in treating bird flu
The avian influenza viruses can cause a mild form ofinfection in humans too, but this thing must be
the disease that does not kill the infected birds, andstudied more.
it only reduces the egg production, and a highlyThe H5N1 virus is one of the most lethal subtypes of
virulent form that can lead to death within 48 hoursthe influenza "A" virus. In the last few years, in Asia,
by multiple internal organ lesions.H5N1 caused millions of deaths among domestic birds
Type A of influenza virus has many differentand hundreds among humans. People got infected
subtypes due to changes in some proteins situatedbecause they got in close contact with the infected
on the surface of the A virus. These changeablepoultry and the contaminated surfaces, but otherwise
proteins are Hemagglutinin (HA) and NeuraminidaseH5N1 remains a rare disease in people and does not
(NA). There exist 16 known HA subtypes and 9 NAspread from human to human.
subtypes of "A" virus, but there are possible manyThere was one case in Indonesia where a family
combinations between HA and NA proteins, leading tomember is suspected to have transmitted the illness
new subtypes. All these subtypes can now be foundto the other members, but this fact has not been
in birds.sustained scientifically.
Until 1997 nobody knew that the virus can affectScientists are concerned about a possible mutation of
humans, but it has happened to those who havethe virus, leading to a global pandemic, similar to the
been in close contact with infected poultry. Until now,Spanish flu pandemic of 1918-1919 when 40-50 million
no cases of human to human transmission of thepeople died.
infection were registered.Doctors have discovered that H5N1 virus is resistant
Human influenza viruses generally refer to thoseamantadine and rimantadine, two antiviral drugs used
subtypes that can infect only humans. There arefor treating human influenza. There remain
known to exist three "A" subtypes of humanoseltamavir and zanamavir to be tested.